MEET the SPEAKERS

Leandra Baptista

Dra. Leandra Baptista is a professor at Universidade Federal do Rio de Janeiro (Campus Xerem). Her research interest are in translational biomedicine, focusing on mesenchymal stem cells, adipose tissue and obesity.

 

 

 

 

 

Angelo MAGRO

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Dr. Angelo Magro is a professor at the Faculdade de Ciências Agronômicas at UNESP/Botucatu, Brazil. His expertise is on molecular biophysics, especially structural biology and toxinology. Recently, he performed a post-doc at École Normale Supérieure de Cachan focusing on the understanding of viral proteins flexibility and stability.

 

 

Nadia IZADI-PRUNEYRE

nadiaNadia Izadi-Pruneyre is a young leader of a group composed of six scientists (post-doctoral researcher, Ph.D. student, permanent researchers and engineers). The group makes part of the Institut Pasteur’s NMR unit. She has a strong expertise in NMR and biophysical methods. For more than 12 years, she has been studying the structural and molecular aspects of bacterial heme acquisition systems. The results of her work are published in over several high impact publication (PNAS, JACS, JBC, NSB, etc.). As an expert in bacterial heme and iron acquisition systems, she is often invited to review articles and projects, as well as to write book chapters in this field. Dr. Izadi-Pruneyre is a member of the scientific committee of the III br.BIO.fr.


Michael NILGES

research.pasteur.fr_nilges_michaelDr. Nilges is the head of the structural bioinformatics research group at Pasteur Institute. His research focuses on the relationship between sequence, three-dimensional structure, and function of proteins, using, among others, modelling techniques and molecular dynamics simulations. His group also continue the development of software for automated NMR structure calculations, and are collaborating with structural genomics projects and the structure databases. They have established collaborations with experimental groups at the Institute Pasteur and elsewhere, for example, in atomic force spectroscopy, X-ray crystallography, and microscopy. The aim of their research is to complement structural studies (X-rays, NMR, Electron microscopy, and others) with in silico studies, to better determine and predict three-dimensional structures and understand molecular recognition and molecular interactions. The applications of those methods include medically relevant molecular processes, such as infectious diseases, cancer, and the action of general anesthetics.


Eric CASCALES

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PhD in Molecular Microbiology and Biotechnology since 2002,  he is currently the head of the Laboratoire d’Ingénierie des Systèmes Macromoléculaires at the Mediterranean Institute of Microbiology (IMM) at Aix-Marseille Université.  His group is interested on the assembly mechanisms of multi-protein complexes of the bacterial cell envelope. They study the “Type VI secretion system” (T6SS), a nano cross-bow machine involved in bacterial competition. Recently, they have started a new project on the “Type IX secretion system” (T9SS) in the human oral pathogen Porphyromonas gingivalis. For both projects they are using a combination of genetic, microscopy, biochemical and biophysical approaches.

For more, check his recent publications at http://www.cascaleslab.fr/publications/ 


Christophe GUILHOT

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Since 2000, Dr. Guilhot leads a team at the Institut de Pharmacologie et Biologie Structurale (IPBS) in Toulouse. Over the last 20 years, he has developed a strong expertise in the genetic engineering of mycobacteria, including Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis. He pionnered the work on the molecular mechanisms of action of mycobacterial lipids during host/pathogen interaction.

Among the key players of Mtb pathogenesis are a large set of unique lipids that are incorporated into its cell envelope. His team has focused its work on the role of cell envelope compounds on the interaction of pathogenic mycobacteria with the host. His team expertises cover the genetic engineering of mycobacteria, the production of recombinant proteins, biochemistry of lipids, cellular and molecular microbiology. They employ state-of-the-art technologies (mass spectrometry, microscopy, BSL3 laboratories and animal facilities…) on their projects.